Compatibility of alcohol and antibiotics

Many have a question, can I drink alcohol when taking antibiotics. Because it is believed that the drugs lose their effectiveness if taken together with alcohol. Another point of view States that alcohol and antibiotics not compatible and it are a deadly combination.

alcohol and antibiotics

Ethanol and antibiotics: similar side effects

Alcohol poisons the cells of the body, inhibiting their ability to recover and to regenerate, leads to fatigue and dehydration, which adversely affects a sick body. And although the alcohol is not completely reduces to zero the effect of the drugs, the healing process slows down. This is one reason why you can't drink alcohol with antibiotics. Since beer is also a kind of alcohol, says it all about alcohol and antibiotics, of course, applies to beer and is the answer to the question of whether beer with antibiotics.

Also the use of alcohol during treatment with antibiotics can produce adverse effects on health: in their interaction within the body might produce undesirable results. Which one, depends not only on the type of alcohol and antibiotics (e.g., antibiotics and beer), but also from individual characteristics of the organism, particularly metabolism.

Alcohol and antibiotics are similar in nature to the effect on the human metabolism and have some similar side effects: dizziness, drowsiness, and upset stomach. That's why if you drink alcohol with antibiotics, alcohol may increase the side effects of drugs.

Some antibiotics suppress the Central nervous system, causing drowsiness, dizziness, weakness, confusion. Alcohol is also a depressant of the Central nervous system. With antibiotic treatment, the side effects intensified. It is fraught with dangerous consequences while driving a car (which in itself is unacceptable, if people drank) and for the elderly who often take multiple different types of medications. Including relieving anxiety, restlessness, strong painkillers, tranquilizers.

Effect on hepatic enzymes

Ethanol and many antibiotics are broken down by the same enzymes that are produced in the liver. If you ask the question, is it possible to drink alcohol in combination with antibiotics, then you should know that under the simultaneous influence of these two substances production of the enzyme can be stopped. This means that neither alcohol nor any drug will not be fully degraded and excreted from the body, which can lead to serious consequences. Among them is the accumulation of alcohol in the blood and increase it to dangerous health level, which increases the possibility of poisoning.

May be another picture when the abuse of alcohol, liver enzymes become overactive. This means that during treatment with antibiotics so quickly they will decompose cure that the antibiotic will be excreted from the body is not producing the desired therapeutic effect.

welcome antibiotique alcohol

When the ban is categorical

Some people still break the rules and drink alcohol during treatment with antibiotics. But they should know that there are medicines to mix that with alcohol is strictly forbidden: when interacting with alcohol, they lead to unpleasant side effects. These include:

  • Metronidazole.
  • Tinidazole.
  • Ethionamide.
  • Cycloserine.
  • Cefotetan.
  • Thalidomide.

Metronidazole is issued for the treatment of dental and vaginal infections, ulcers and bedsores. Tinidazole is assigned to the same cases, and metronidazole, as well as for the treatment of infections of the gastrointestinal tract. Cefotetan treat infections of the lungs, gastrointestinal tract, bones, joints, blood, urinary tract and skin.

Is antibiotics in interaction with alcohol cause severe cramps in the stomach, nausea, vomiting, headache, rush of blood to the head, chest pain, tachycardia.

All of the above symptoms are practically identical with the side effects, which causes ingredient disulfiram, which is used for the treatment of alcoholism method of medical coding. In the treatment of disulfiram even small doses of alcohol sufficient to cause these symptoms.

In the treatment of metronidazole, tinidazole and cum cefotetan should be completely avoided from the use of alcoholic drinks. It is necessary to refrain from their use for three days after the last dose of antibiotics.

The effect of the combination of drugs with alcohol

Compatibility of antibiotics and alcohol, it becomes clear from the table below, which describes the effect of their interaction. It will allow to understand whether you can drink alcohol with antibiotics and alcohol can adversely affect the body:

the ban on antibiotics
Acting substance The effect of the combination with alcohol Recommendation



Bouts of flushing and redness of the skin,




Avoid alcohol in the treatment of sulfamethoxazole/trimethoprim
Metronidazole, Tinidazole, Cefotetan Disulfirame reactions:

cramps in abdominal region,



headache, flushing.

Avoid alcohol during treatment and for 72 hours after the last ingestion of metronidazole, tinidazole, cefotetan
Linezolid Increased risk of hypertension Avoid drinking alcoholic beverages, primarily containing tyramine (beer, vermouth, wine red)
Rifampin The risk of liver toxicity Do not consume with alcohol
Isoniazid Increased risk of liver toxicity if daily alcohol consumption Avoid drinking alcohol with the substance
Cycloserine The combination with alcohol may lead to intoxication of the Central nervous system, seizures and convulsions Avoid drinking alcohol with cycloserine
Ethionamide Possible toxicity of the Central nervous system, the development of psychosis Avoid alcohol during treatment with ethionamide
Voriconazole Changes in the metabolism of the liver Avoid alcohol during treatment
Ketoconazole Possible liver toxicity and the emergence of disulfiramum reactions:

cramps in abdominal region,




tides of blood.

Avoid drinking alcohol during treatment with ketoconazole
Pyrazinamide The possible toxicity of the liver Treatment with pyrazinamide is prohibited alcoholics or regularly drunk
Thalidomide Increases the risk enhance the sedative side effects of thalidomide are drowsiness, confusion. Not to use drivers and machine operators. Avoid alcohol during treatment with thalidomide

There are antibiotics that do not cause a very negative effect in non-drinker or rarely drink alcohol. But can cause dangerous side effects in chronic alcoholics (this includes drinking beer) and systematically drinkers.

The ban violated: what to do?

If we talk about what will happen if the ban was broken and people took simultaneously to the antibiotics and alcohol, then you should know that the strength of the side effects depends on overall health, the amount of alcohol consumed, the ability of the liver to dispose of these substances. Not all the consequences have been pronounced, but in the worst case can be fatal.

If the ban was broken, and there was an adverse reaction should immediately call an ambulance. This is the only correct exit in case of occurrence of the effects of blending ethanol with antibiotics. Severe symptoms after antibiotics and alcohol are:

antibiotics and alcohol
  • shallow breathing;
  • chest pain;
  • irregular heartbeat;
  • dizziness;
  • nausea;
  • vomiting.

Since the probability of interaction of alcohol and antibiotics can lead to fatal, the appearance of the aforementioned symptoms requires immediate medical intervention. If you leave a person with these symptoms, without timely medical care, the consequences can be fatal. For example, an arrhythmia can lead to heart failure and dehydration due to vomiting is a cause of lowering pressure to dangerous levels.